- The Initial Assessment
- The Golden Minute and Escalation
The Golden Minute and Escalation
The Golden Minute framework
The Golden Minute should be viewed as an outer limit rather than a full 60-second countdown (if a newborn is not responding adequately at any stage, intervention must not be delayed). If an infant is not breathing adequately or has a heart rate below 100 bpm at any point during or after the initial steps, PPV should begin without waiting for the 60-second mark.
The sequence within the Golden Minute is shown in Figure 2.

Supplemental oxygen and SpO₂ targets
Free-flow supplemental oxygen may be appropriate for an infant who is breathing spontaneously but has persistent central cyanosis and a heart rate above 100 bpm. It is not a substitute for PPV in an infant with inadequate respiratory effort or bradycardia.
Healthy term newborns take several minutes to reach adult SpO₂ levels; therefore, applying adult targets in the delivery room means giving oxygen unnecessarily. Use Table 6.
Minute of life | Target SpO₂ (preductal) |
|---|---|
1 | 60–65% |
2 | 65–70% |
3 | 70–75% |
4 | 75–80% |
5 | 80–85% |
6 | 85–95% |
Pulse oximetry should be placed on the right hand or wrist (the preductal position) to obtain an accurate reading during resuscitation. Left-hand or lower-limb readings are postductal and will not reflect cerebral oxygen delivery.
Meconium-stained amniotic fluid
Current guidelines are unambiguous on MSAF: routine intrapartum suctioning is out, regardless of meconium consistency. Routine intrapartum suctioning of the oropharynx is no longer recommended regardless of meconium consistency.
For a vigorous infant (defined as one with good tone, strong respiratory effort, and a heart rate above 100 bpm), proceed with routine initial steps without suctioning. For a depressed infant (absent or poor tone, inadequate respiratory effort, or bradycardia), intubation and tracheal suctioning should be considered before initiating PPV, using clinical judgment based on the degree of depression and available resources.
Escalation decision at 60 seconds
At the end of the Golden Minute, one of three responses should be apparent:
- Heart rate ≥100 bpm and adequate breathing: continue observation, wean supplemental oxygen, transfer to routine care
- Heart rate ≥100 bpm, but breathing inadequate: initiate PPV
- Heart rate <100 bpm regardless of respiratory effort: initiate PPV immediately
Any infant who has not achieved a heart rate of 100 bpm or above with adequate spontaneous breathing by 60 seconds requires positive-pressure ventilation. This is the primary escalation threshold in neonatal resuscitation.
Medically reviewed by: Kim Murray, RN, MS., Medical Educator
