- ACLS BLS for Adults
- Initiating the Chain of Survival
- 2025 BLS Guideline Changes
- One Rescuer Adult BLS CPR
- Two Rescuer Adult BLS CPR
- Adult Mouth-to-Mask and Bag-Mask Ventilation
- Adult Basic Life Support (BLS) Algorithm
- BLS for Children/Infants
- CPR Steps for Children
- One-Rescuer BLS/CPR for Infant (newborn to age 12 months)
- CPR Steps for Infants
- Child/Infant Mouth-to-Mouth Ventilation
- ACLS Cases Respiratory Arrest
- Pulseless Ventricular Tachycardia and Ventricular Fibrillation
- Pulseless Electrical Activity Asystole
- Adult Cardiac Arrest Algorithm
- Post-Cardiac Arrest Care
- Adult Immediate Post-Cardiac Arrest Care Algorithm
- Symptomatic Bradycardia
- Adult Bradycardia with Pulse Algorithm
- Tachycardia
- Stable And Unstable Tachycardia
- Adult Tachycardia With Pulse Algorithm
- Acute Coronary Syndrome
- Acute Coronary Syndrome Algorithm
- Acute Stroke
- Acute Stroke Algorithm
Pulseless Electrical Activity Asystole
Pulseless electrical activity (PEA) and asystole are related cardiac rhythms in that they are both life‐threatening and unshockable cardiac rhythms. Asystole is a flat‐line ECG (Figure 25). There may be a subtle movement away from baseline (drifting flat‐line), but there is no perceptible cardiac electrical activity. Always ensure that a reading of asystole is not a user or technical error. Make sure pads have good contact with the individual, leads are connected, the gain is set appropriately, and the power is on. PEA is one of many waveforms by ECG (including sinus rhythm) without a detectable pulse. PEA may include any pulseless waveform with the exception of VF, VT, or asystole (Figure 26).
Hypovolemia and hypoxia are the two most common causes of PEA. They are also the most easily reversible and should be at the top of any differential diagnosis.
If the individual has a return of spontaneous circulation (ROSC), proceed to post‐cardiac arrest care.
RULES FOR PEA AND ASYSTOLE
A flatline ECG reveals no electrical activity and is reserved for asystole, whereas PEA reveals organized or semi-organized electrical activity in the absence of a palpable pulse.
Figure 25| ORGANIZED OR SEMI-ORGANIZED | Any rhythm without a pulse. |
| RATE | Any rate or no rate. |
| P WAVE | Possible P wave or none detectable. |
| PR INTERVAL | Possible PR wave or none detectable. |
| QRS | Possible QRS complex or none detectable. |
| ASYSTOLE REGULARITY | The rhythm will be a nearly flat line. |
| RATE | There is no rate. |
| P WAVE | There are no P waves present. |
| PR INTERVAL | PR interval is unable to be measured due to no P waves being present. |
| QRS | There are no QRS complexes present. |
REVERSIBLE CAUSES
Figure 26 76
REVERSIBLE CAUSES OF CARDIAC ARREST | |
|---|---|
| THE H’S | THE T’S |
| Hypovolemia | Tension pneumothorax |
| Hypoxia | Tamponade |
| H+ (acidosis) | Toxins |
| Hypo/Hyperkalemia | Thrombosis (coronary) |
| Hypoglycemia | Thrombosis (pulmonary) |
| Hypothermia | Trauma (unrecognized) |
Always verify that a reading of asystole is not an equipment failure. Make sure pads make good contact with the individual, all cables are connected, the gain is set appropriately, and the power is on.
Hypovolemia and hypoxia are easily reversed and are the two most common causes of PEA.
NO ATROPINE DURING PEA OR ASYSTOLE
Although there is no evidence that atropine has a detrimental effect during bradycardia or asystolic cardiac arrest, routine use of atropine during PEA or asystole has not been shown to have a therapeutic benefit. Therefore, the ILCOR has removed atropine from the cardiac arrest guidelines.
EPINEPHRINE REMAINS STANDARD TREATMENT FOR CARDIAC ARREST
There have been no new studies in the past 5 years comparing epinephrine to a placebo since the 2020 ACLS guidelines were published. Earlier studies consistently show that epinephrine strongly improves the chance of getting a pulse back, surviving to hospital admission, and surviving to hospital discharge. Although epinephrine has not been shown to improve neurological outcomes, it does increase short-term survival, which is necessary for any meaningful recovery. Because there is no practical way during a cardiac arrest to predict who will have a good neurological outcome, epinephrine remains the standard treatment for cardiac arrest.
